Monday, August 18, 2008


The Somatotrophic Axis in Brain Function

Publisher: Academic Press
Number Of Pages: 384
Publication Date: 2005-08-12
ISBN-10 / ASIN: 0120884844
ISBN-13 / EAN: 9780120884841
Binding: Hardcover

Product Description:
The somatotropic axis is one of the major hormonal systems regulating postnatal growth in mammals. It interacts with the central nervous system on several levels. Growth hormone (GH) and insulin-like growth factor-I (IGF-I) receptors are expressed in many brain areas including the hippocampus, pituitary and hypothalamus. GH and IGF-I are important factors in the development and differentiation of the CNS and have protective properties in dementia, as well as in traumatic and ischaemic injury of the CNS. Also GH has an important impact on mood and well-being with GH secretory capacity being reduced in depression.

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